Coronary Physiology

About

Invasive coronary physiology is a key instrument in decision making for the interventional cardiologist.

Fractional flow reserve (FFR) has been well validated in chronic stable coronary artery disease. FFR is the ratio of the pressure distal to a lesion relative to the aorta pressure during maximal hyperaemia. Its practical applications are expanding into other clinical situations, including acute coronary syndrome, severe aortic stenosis and post percutaneous coronary intervention.

Instant wave-free ratio (iFR) is a resting index used to assess severity of an intracoronary stenosis. It measures the ratio of mean coronary pressure distal to a stenosis to the mean aortic pressure during an isolated period of diastole – the “wave-free period”.

It is an attractive alternative to FFR because it does not require hyperaemia, and therefore has a lower incidence of patient discomfort, side-effects, and shorter procedural time.

Articles

Latest Advances in Cardiac CT

Published:

26 February 2020

Citation:

European Cardiology Review 2020;15:e01.

Improvement of Fractional Flow Reserve after Percutaneous Coronary Intervention Does Not Necessarily Indicate Increased Coronary Flow

Citation:

European Cardiology Review 2019;14(1):10–2

Assessing the Haemodynamic Impact of Coronary Artery Stenoses: Intracoronary Flow Versus Pressure Measurements

Citation:

European Cardiology Review 2018;13(1):46–53.

Guest Editorial: Controversies in Fractional Flow Reserve

Citation:

European Cardiology Review 2016;11(2):83–4